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Pharmaceutical Industry

We Should Vaccinate Children in High-income Countries Against COVID-19, Too

Written by Lisa Forsberg, Anthony Skelton, Isra Black

In early September, children in England, Wales and Northern Ireland are set to return to school. (Scottish schoolchildren have already returned.) Most will not be vaccinated, and there will be few, if any, measures in place protecting them from COVID-19 infection. The Joint Committee on Vaccination and Immunisation (JCVI) have belatedly changed their minds about vaccinating 16- and 17-year olds against COVID-19, but they still oppose recommending vaccination for 12-15 year olds. This is despite considerable criticism from public health experts (here, here, and here), and despite the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) declaring COVID-19 vaccines safe and effective for children aged 12 and up—Pfizer/BioNTech in the beginning of June, and Moderna the other week.

In Sweden, children returned to school in the middle of August. As in the UK, children under 16 will be unvaccinated, and there will be few or no protective measures, such as improved ventilation, systematic testing, isolation of confirmed cases, and masking. Like the JCVI in the UK, Sweden’s Folkhälsomyndigheten opposes vaccination against COVID-19 for the under-16s, despite Sweden’s medical regulatory authority, Läkemedelsverket, having approved the Pfizer and Moderna vaccines for children from the age of 12. The European Medicines Agency approved Pfizer and Moderna in May and July respectively, declaring that any risks of vaccine side-effects are outweighed by the benefits for this age group.

Read More »We Should Vaccinate Children in High-income Countries Against COVID-19, Too

What’s Wrong With Giving Treatments That Don’t Work: A Social Epistemological Argument.

Let us suppose we have a treatment and we want to find out if it works. Call this treatment drug X. While we have observational data that it works—that is, patients say it works or, that it appears to work given certain tests—observational data can be misleading. As Edzard Ernst writes:

Whenever a patient or a group of patients receive a medical treatment and subsequently experience improvements, we automatically assume that the improvement was caused by the intervention. This logical fallacy can be very misleading […] Of course, it could be the treatment—but there are many other possibilities as well.Read More »What’s Wrong With Giving Treatments That Don’t Work: A Social Epistemological Argument.

Trust, mistrust, and science – finding the balance between conspiracy theories and naïve trust

Scientific illiteracy and “anti-science”-beliefs are a common topic in scientific and academic communities. For example, how most (or many) Americans do not understand the difference between DNA and a genetically modified food. Another known topic is, for example, skepticism towards vaccinations. In this editorial of the biggest Finnish newspaper, the author predicts that the new rise of the Middle Ages is upon us if people refuse to trust scientific results, and emotions continue to rule out reason.

While excessive skepticism and building conspiracy theories against science might, by and large, be irrational and, most importantly, harmful, the phenomenon deserves a deeper consideration than accusations of irrationality, emotionality, or stupidity.

An important reason for the need of deeper elaboration is in the following controversy: on the one hand, the scientific community, rightly, calls for trust to scientific work. Enormous accomplishments of biomedical science are a great argument for trusting science and its capability to improve life. However, on the other hand, there is strong evidence that the scientific community is not always trustworthy. Medical companies, the paramount founder of medical research, have faced many accusations of scientific misconduct and fraud (how funding affects outcomes – see also this and this -, ghostwriting, corruption). Furthermore, there is discussion about how FDA reacts to questionable and even unreliable scientific papers. It is claimed that despite the knowledge about scientific misconduct, the FDA does little to report the questionable results to physicians and medical researchers. And there is at least much evidence to discuss good practices concerning e.g. Monsanto and how things work with GMO agriculture. “What companies do is not the problem of science” is a legitimate sentence when discussing only the mere possible existence of some biomedical or GMO innovation, but when brought to a concrete level, the real-life questions should be taken back to the issue.Read More »Trust, mistrust, and science – finding the balance between conspiracy theories and naïve trust

Conventional and non-conventional medicine and the Placebo Paradox

Alternative medicine is a trendy topic to discuss – both by despising and praising it in a contradictory manner. But there is something controversial in the categorical critique towards it. The controversies and fallacies in the categorical praise are much elaborated and I will mostly leave aside that part.Read More »Conventional and non-conventional medicine and the Placebo Paradox

Howick on What Counts as a Placebo

The use of placebos in medicine raises a large number of serious ethical issues. Do they involve deceiving patients, or violating their autonomy in some way? Are they harmful to certain patients, in research trials where the actual treatment being trialled is thought likely to be successful? Can placebos – if medically warranted – be funded through a health care budget? All these questions require us to be able to say what a placebo is, and that is more tricky than one might think.Read More »Howick on What Counts as a Placebo

I’ve warned you! But I shouldn’t have

Among close friends, or even within the family, the use of SSRI’s (selective serotonin reuptake inhibitors) can be a delicate topic, it may come with connotations of depression, suicidal behaviour, and can be emotionally marginalizing. A new scientific review may further entangle this already vexing situation, in the study (Isacsson, G. & Alhner, J. 2013)… Read More »I’ve warned you! But I shouldn’t have

Should you take ecstasy to improve your marriage? Not so fast …

Love drugs and science reporting in the media: Setting the record straight 

By Brian D. Earp, Julian Savulescu, and Anders Sandberg

Love. It makes the world go round. It is the reason we have survived as a species. It is the subject of our art, literature, and music—and it is largely the product of chemical reactions within the brain.

No wonder science is starting to unravel the ways in which we can influence it, and perhaps even control it.

Just as Darwin’s finding that we are descended from apes shocked people in the nineteenth century, so people will be shocked to find that our most lofty social ideal is something we share with our mammalian cousins and which is the subject of scientific scrutiny and even chemistry-book manipulation.

In 2008, two of us (Julian Savulescu and Anders Sandberg) published an article in the journal Neuroethics on the topic of “love drugs” – a term we use to refer to pharmacological interventions based on existing and future bio-technologies that could work to strengthen the bond between romantic partners. All three of us have an article just published in the journal Philosophy & Technology in which we build upon that earlier work. Interested readers will take the time to study those papers in full, but we have a feeling that much of the population will stop at a handful of media reports that have recently summarized our ideas, including at least one article that we think has the potential to mislead. Let us set the record straight.

Read More »Should you take ecstasy to improve your marriage? Not so fast …

Love and other drugs, or why parents should chemically enhance their marriages

By Brian Earp

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Love and other drugs, or why parents should chemically enhance their marriages

Valentine’s day has passed, and along with it the usual rush of articles on “the neuroscience of love” – such as this one from Parade magazine. The penner of this particular piece, Judith Newman, sums up the relevant research like this:

It turns out that love truly is a chemical reaction. Researchers using MRIs to look at the brain activity of the smitten have found that an interplay of hormones and neurotransmitters create the state we call love.

My humble reckoning is that there’s more to “the state we call love” than hormones and neurotransmitters, but it’s true that brain chemistry is heavily involved in shaping our experience of amour. In fact, we’re beginning to understand quite a bit about the cerebral circuitry involved in love, lust, and human attachment—so much so that a couple of Oxford philosophers have been inspired to suggest something pretty radical.

They think that it’s time we shifted from merely describing this circuitry, and actually intervened in it directly—by altering our brains pharmacologically, through the use of what they call “love drugs.”

Read More »Love and other drugs, or why parents should chemically enhance their marriages

Good Grief?

In book 4 of Homer’s Odyssey, Odysseus’s son Telemachos arrives in Sparta to quiz Menelaos on whether Odysseus is still alive and if so where he might be. Menelaos reduces everyone (including himself) to tears by telling everyone how sad he is that Odysseus hasn’t made it home. He then says it’s time for them… Read More »Good Grief?

Counterfeit Placebos

Last week it was reported that police in Bangladesh had made a major bust at a factory that was producing counterfeit homeopathic drugs. The counterfeiters were attaching the labels of other drug producers to the remedies they were producing in their own factory. Dhaka's Daily Star reported the bust with the rather ironic headline "Fake Medicine Factory Busted".

Of course, even homeopathic remedies need to be guaranteed safe if they are sold in stores, and counterfeiters are not bound by the same safety controls as other more reputable sources. There are also 'intellectual property' issues concerning the use of other company's labels and trademarks. So I am not here to tell you that this drug bust was unnecessary or ridiculous. In fact I want to challenge The Star's implicit suggestion that homeopathic remedies are by their nature counterfeit therapies.

Read More »Counterfeit Placebos