synthetic biology

Strange brew: opiates from yeast

A recent series of papers have constructed a biochemical pathway that allows yeast to produce opiates. It is not quite a sugar-to-heroin home brew yet, but putting together the pieces looks fairly doable in the very near term. I think I called the news almost exactly five years ago on this blog.

People, including the involved researchers, are concerned and think regulation is needed. It is an interesting case of dual-use biotechnology. While making opiates may be somewhat less frightening than making pathogens, it is still a problematic use of biotechnology: millions of people are addicted, and making it easier for them to get access would worsen the problem. Or would it?

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Personalised weapons of mass destruction: governments and strategic emerging technologies

Andrew Hessel, Marc Goodman and Steven Kotler sketches in an article in The Atlantic a not-too-far future when the combination of cheap bioengineering, synthetic biology and crowdsourcing of problem solving allows not just personalised medicine, but also personalised biowarfare. They dramatize it by showing how this could be used to attack the US president, but that is mostly for effect: this kind of technology could in principle be targeted at anyone or any group as long as there existed someone who had a reason to use it and the resources to pay for it. The Secret Service looks like it is aware of the problem and does its best to swipe away traces of the President, but it is hard to imagine this to be perfect, doable for old DNA left behind years ago, or applied by all potential targets. In fact, it looks like the US government is keen on collecting not just biometric data, but DNA from foreign potentates. They might be friends right now, but who knows in ten years…

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