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Regulation

The New Law on Admixed Embryos and the Genetic Heritage of the Living Kingdom

Scientists in the US recently created a fluorescent human embryo. This was achieved by inserting a gene for green fluorescent protein. This shows that it is possible to successfully transfer a gene from a non-human animal to a human and for that gene to express its function. Other animal studies have shown that such gene transfer is both safe and effective, creating super animals, such as mice with colour-vision derived from human genes transferred.

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Saviour Siblings Saved!

Two attempts to amend the Human Fertilisation and Embryology Bill’s provision to allow ‘saviour siblings’ failed in the House of Commons yesterday. The first attempt was to block the practice and failed 342 to 163. The second attempt was to limit the provision to life-threatening cases. It was defeated 318 to 149. As it stands the Bill allows embryo testing and hence selection for ‘saviour siblings’ provided that “there is a significant risk that a person [the sibling ‘to be saved’] … will have or develop a serious physical or mental disability, serious illness or any other serious medical condition.”

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The Ethics of ‘Human Admixed Embryos’: Concerns and Responses

By Loane Skene, Professor of Law, University of Melbourne and Julian Savulescu,  Uehiro Chair in Practical Ethics and Director Uehiro Centre for Practical Ethics, University of Oxford

The Human Fertilisation and Embryology Authority (HFEA) Bill, currently before the UK Parliament, will, if passed, permit HFEA to license the creation for research of embryos that combine human and animal genetic material (called, in the Bill, ‘human admixed embryos’). These embryos include cybrids which are formed by inserting the nucleus of a human body cell into an animal egg that has had its nucleus removed. Cybrids would produce embryonic stem cells that are 99.9% human. The Bill would also permit other types of embryos to be formed from human and animal genetic material that would be up to half animal. This post explains why scientists want to create human admixed embryos. It then outlines some ethical concerns about the creation of these embryos and responses that may be made to those concerns.

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Looking for Biopolitical Trouble

Researchers at Cornell university have
developed a genetically modified human embryo expressing a green fluorescent
protein. This is a technology already demonstrated
in animals (and plants), including monkeys. But the news that it had been done to a
human embryo has stirred up reactions worrying about designer babies. Are we
already in a brave new world of designer babies? And how should we handle the biopolitical debate?

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Football screens and genes: Should genetic discrimination in sport be banned?

In the Guardian this weekend, it is reported that at least one UK football club has been contemplating using genetic tests to screen potential recruits,in the hope of identifying future star players. This comes only one day after legislation was passed in the US Senate prohibiting insurance companies and employers from using genetic information in hiring or insurance decisions.

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Do we own our bodies? Should we?

There was a sad story last week about a young woman who died unexpectedly at the age of 19.   She was on the organ donor register, and her own mother was on the waiting list for a kidney donation, but the mother was refused one of the kidneys.  Even the transplant coordinator was ‘crying her eyes out’, but there was apparently no escape.  Rules were rules.  Cadaveric donations must go impartially and anonymously to the most compatible people at the top of the waiting list, and the authorities decreed that these organs must go to three strangers – whose identity the mother will never even know.

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