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Reproductive Technologies

Cloning and animal exploitation

The Daily Mail reports this morning that 8 clone-offspring cows have been born in the UK. Also today, the first survey of public opinion on ‘clone farming’ has been released indicating significant unease and opposition to the idea of meat products or milk from cloned sources.

There are strict prohibitions on reproductive cloning for humans in most countries (for example, the recently debated HFEA bill in the UK, and the Human reproductive Cloning Act 2001). However there are few, if any, constraints on the cloning of animals. Is this the start of a new era of animal exploitation?

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Legal Abortion Time-Limits: Arbitrary Limits Harm Women

By Dr. Lachlan de Crespigny, Department of Obstetrics and Gynaecology, University of Melbourne

The vote by the British parliament to keep the upper legal limit on abortion at 24 weeks was headline news around the world. An article in The Economist (1) considers that the British were spared America’s abortion wars partly because Britain is less religious than America, but also because abortion laws are made in Parliament, where shades of grey can be debated, not in the courts, where black or white usually prevails.

Interestingly much of the debate was about ‘viability’ – the minimum gestational age at which a newborn is said to be capable of surviving with modern intensive care facilities. This is a simple across-the-board week count. But the survival rate of newborns also depends on many other factors, including where they are born (2, 3), fetal health including the presence or absence of an abnormality (which remains lawful where the child will be ‘seriously handicapped’), plus the condition of the newborn. While around half or so of 24 week newborns in Britain may survive, many or most of the abortions at around that gestation are of problem, or unhealthy, pregnancies.

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HFEA and Regulating Reproduction:Triumph for Rationality and Victory for Secular Ethics

MPs voted on Tuesday on two of the most controversial issues surrounding reproduction- the provision of IVF treatment, and the availability of legal abortion. Under the new laws, IVF clinics will no longer have a legal requirement to consider the need for a father, but will instead be asked to ensure provision of ‘supportive parenting’, removing any barrier to single women and lesbian couples conceiving through the treatment. In a separate amendment, MPs were asked to consider the legal time limit on abortion, which currently stands at 24 weeks. Given the option to reduce this limit to 22, 20 or even just 12 weeks, MPs voted by a comfortable majority to stick with the status quo. 

The UK is now at the forefront of rational reform to legislation governing reproduction and research. The Human Fertilisation and Embryology Bill has now approved the creation of human admixed embryos, with important implications for scientific advance.

Blog on Admixed Embryos
Savulescu, J., The Case for Creating Human -Non Human Cell Lines, Bioethics Forum
Human Enhancement papers, media and other resources for free download

It has also reformed the regulation of reproduction in a thoroughly sensible manner.

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Saviour Siblings Saved!

Two attempts to amend the Human Fertilisation and Embryology Bill’s provision to allow ‘saviour siblings’ failed in the House of Commons yesterday. The first attempt was to block the practice and failed 342 to 163. The second attempt was to limit the provision to life-threatening cases. It was defeated 318 to 149. As it stands the Bill allows embryo testing and hence selection for ‘saviour siblings’ provided that “there is a significant risk that a person [the sibling ‘to be saved’] … will have or develop a serious physical or mental disability, serious illness or any other serious medical condition.”

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Viability and the abortion debate – what really matters?

MPs in the House of Commons will debate tomorrow whether the cut-off for legal abortions in the UK should be reduced. Currently abortions are permitted up to the 24th week of a pregnancy, and some MPs have argued that this should be reduced to 20 weeks or below. Advocates and opponents of the change have pointed to scientific evidence about the viability of infants born extremely prematurely at 22, 23 and 24 weeks. They seem to believe that if we can answer the scientific question of whether such infants are viable, that will resolve the question about whether or not abortion is permissible at that stage.
That might be the case if there were a consensus on what viability means, and why it is important in questions about abortion time-limits. But, as this article will highlight, there is no such consensus, and it is not straightforward why viability should matter. So far in this public debate there has been little or no mention of the important questions – what is viability, and why is it important in abortion law?

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Humane Evolution

Professor John Harris wonders Who’s afraid
of a synthetic human? in the Times. He argues we should support
the Human Fertilisation and Embryology Bill because it will help us develop
effective therapies and enhance ourselves. Science is about bettering our lot,
after all. In particular, he says, synthetic biology may help us avoid going
extinct due to our vulnerabilities and instead enable us to choose (or become)
our successors as a species.

Many people become confused by the
possibility of a posthuman future. The traditional view of the future is a
stark one: either humanity extinct, or humans roughly as they are today. The
posthuman options would be that we either change ourselves so radically that
the resulting species is so  fundamentally different from humanity that we
would regard it as something entirely new, or that we create some kind of independent
beings that continue our culture even as traditional humanity retires from the
forefront (hopefully as proud parents of the new beings). The range of possible
options within these scenarios is endless, inviting equally endless and loud
speculation. That tends to distract from the key message of Harris’ essay: we
are leaving the realm of natural evolution and entering what he calls a realm
of enhancement evolution.

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The Ethics of ‘Human Admixed Embryos’: Concerns and Responses

By Loane Skene, Professor of Law, University of Melbourne and Julian Savulescu,  Uehiro Chair in Practical Ethics and Director Uehiro Centre for Practical Ethics, University of Oxford

The Human Fertilisation and Embryology Authority (HFEA) Bill, currently before the UK Parliament, will, if passed, permit HFEA to license the creation for research of embryos that combine human and animal genetic material (called, in the Bill, ‘human admixed embryos’). These embryos include cybrids which are formed by inserting the nucleus of a human body cell into an animal egg that has had its nucleus removed. Cybrids would produce embryonic stem cells that are 99.9% human. The Bill would also permit other types of embryos to be formed from human and animal genetic material that would be up to half animal. This post explains why scientists want to create human admixed embryos. It then outlines some ethical concerns about the creation of these embryos and responses that may be made to those concerns.

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Looking for Biopolitical Trouble

Researchers at Cornell university have
developed a genetically modified human embryo expressing a green fluorescent
protein. This is a technology already demonstrated
in animals (and plants), including monkeys. But the news that it had been done to a
human embryo has stirred up reactions worrying about designer babies. Are we
already in a brave new world of designer babies? And how should we handle the biopolitical debate?

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Lesbians and male role models

In Britain, the Conservative Party has challenged the government to block lesbian couples from receiving IVF treatment unless they can provide a ‘male role model’ for their child. This is part of a proposed amendment to the human fertilisation and embryology bill which is currently before the parliament. Such a change would be a very bad idea.

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The viability of fetuses and the abortion debate

A paper has been published online in the British medical journal today
suggesting that survival of extremely premature infants (less than 24
weeks gestation) has not improved in the last decade. This comes less
than a week before a debate in the House of Commons on the Human
Fertilisation and Embryo Authority bill. It has been claimed that this
paper “completely blows out of the water” the arguments of
anti-abortion MPs who hope next week to push for a reduction in the
cut-off for legal abortion (currently 24 weeks).

Read More »The viability of fetuses and the abortion debate