Video Series: John Harris Defends Gene-Editing in Human Embryos

Novel gene editing technologies, such as CRISPR/Cas9, allow scientists to make very precise changes in the genome of human embryos. This could prevent serious genetic diseases in future children. But the use of gene editing in human embryos also raises questions: Is it safe? Should prospective parents be free to choose the genetic characteristics of their children? What if they want to use gene editing to have a deaf child, or a child with fair skin and blue eyes? Should gene editing be regulated globally, or should each country have their own legislation? In this interview with Katrien Devolder, John Harris (Professor Emeritus, University of Manchester &  Visiting Professor in Bioethics, King’s College London) answers these and other questions, and defends the view that we have the strongest moral obligation to gene-edit human embryos, not only to prevent disease but also for the purpose of enhancement.

Super Soldiers, Civ-Mil Relations, and the 21st Century Coriolanus

Written by Michael Robillard


            “Let me have war, say I: it exceeds peace as far as day does night; it’s spritely, waking, audible, and full of vent. Peace is a very apoplexy, lethargy; mulled, deaf, sleepy, insensible; a getter of more bastard children than war’s a destroyer of men.”
William Shakespeare, The Tragedy of Coriolanus

As 21st century technology continues to progress at an ever alarming pace, the science-fiction notion of ‘human enhancement’ looks, day by day, to be an ever-approaching reality. Neuro-chemical enhancement, genetic enhancement, man/machine pairing; each of these emerging technologies carries with it, both individually and collectively, a host of ethical worries concerning the well-being, autonomy, and identity of the individual person. These ethical worries arguably become even more problematic and complex when considering the specific enhancement of soldiers.

In addition to the many ethical concerns surrounding human enhancement in general, the issue of soldier enhancement in particular appears to come with its own set of unique moral problems. This is so, at least in part, since the role of soldier often requires the promotion of attributes, aspects of character, and capacities that are arguably virtuous within the context of war but potentially vicious within the context of otherwise ‘normal’ society. Indeed, a propensity towards obedience, a disinhibition towards violence, extreme tolerance for risk, and being exceptionally skillful at the trade of killing are not typical attributes we would consider noble or praise-worthy within the day-to-day domestic sphere, though they are attributes absolutely vital for success on the battlefield. Continue reading

Cross Post: Speaking with: Julian Savulescu on the ethics of genetic modification in humans

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Could genetic engineering one day allow parents to have designer babies?
Tatiana Vdb/flickr, CC BY

William Isdale, University of Melbourne

What if humans are genetically unfit to overcome challenges like climate change and the growing inequality that looks set to define our future?

Julian Savulescu, visiting professor at Monash University and Uehiro professor of Practical Ethics at Oxford University, argues that modifying the biological traits of humans should be part of the solution to secure a safe and desirable future.

The University of Melbourne’s William Isdale spoke to Julian Savulescu about what aspects of humanity could be altered by genetic modifications and why it might one day actually be considered unethical to withhold genetic enhancements that could have an overwhelmingly positive effect on a child’s life. Continue reading

Video: Professor Julian Savulescu speaks in the DNA Manipulation Debate at The Oxford Union

The Oxford Union.

The Motion: This House Believes the Manipulation of Human DNA is an Ethical Necessity.

The Speakers: Julian Savulescu closed the case for the Proposition, as the fifth speaker of six in the debate.

When People Work Together is Less More or Less (and is More Less or More)?

Written by Andreas Kappes

This is an unedited version of Andreas Kappes’ article which was originally  published on The Conversation


Doping in sports often gives us intriguing insights not only into how we think about right and wrong1, but also into our intuitions about performance. In the aftermath of the latest doping scandal, for instance, Arsene Wegner, eminent football manager of Arsenal London, accused the Uefa (governing body of European football) of “basically accepting” doping 2. Arsenal London had just lost to Dynamo Kiev and one player form the Ukrainian team was caught doping. Uefa did not punish the Ukrainians, only the perpetrator. But surely, one doped player makes a team better, gives an unfair advantage to them, right? This intuition reflects how most of us think about performance in groups, not only in sports, but group performance everywhere. More of something that enhances individual performance such as expertise or skill is also more success for the team, and more of something that impairs individual performance such as sleep deprivation or stress means also less success for the team. Continue reading

Guest Post: Should the army abandon their zero-tolerance policy on substance use?

Written by Anke Snoek

Macquarie University

In the UK around 500 soldiers each year get fired because they fail drug-testing. The substances they use are mainly recreational drugs like cannabis, XTC, and cocaine. Some call this a waste of resources, since new soldiers have to be recruited and trained, and call for a revision of the zero tolerance policy on substance use in the army.

This policy stems from the Vietnam war. During the First and Second World War, it was almost considered cruel to deny soldiers alcohol. The use of alcohol was seen as a necessary coping mechanism for soldiers facing the horrors of the battlefield. The public opinion on substance use by soldiers changed radically during the Vietnam War. Influenced by the anti-war movement, the newspapers then were dominated by stories of how stoned soldiers fired at their own people, and how the Vietnamese sold opioids to the soldiers to make them less capable of doing their jobs. Although Robins (1974) provided evidence that the soldiers used the opioids in a relatively safe way, and that they were enhancing rather than impairing the soldiers’ capacities, the public opinion on unregulated drug use in the army was irrevocably changed. Continue reading

“The medicalization of love” – podcast interview

Just out today is a podcast interview for Smart Drug Smarts between host Jesse Lawler and interviewee Brian D. Earp on “The Medicalization of Love” (title taken from a recent paper with Anders Sandberg and Julian Savulescu, available from the Cambridge Quarterly of Healthcare Ethics, here).

Below is the abstract and link to the interview:


What is love? A loaded question with the potential to lead us down multiple rabbit holes (and, if you grew up in the 90s, evoke memories of the Haddaway song). In episode #95, Jesse welcomes Brian D. Earp on board for a thought-provoking conversation about the possibilities and ethics of making biochemical tweaks to this most celebrated of human emotions. With a topic like “manipulating love,” the discussion moves between the realms of neuroscience, psychology and transhumanist philosophy.



Earp, B. D., Sandberg, A., & Savulescu, J. (2015). The medicalization of love. Cambridge Quarterly of Healthcare Ethics, Vol. 24, No. 3, 323–336.

Guest Post: Pervitin instead of coffee? Change in attitudes to cognitive enhancement in the 50’s and 60’s in Brazil  


Written by Marcelo de Araujo

State University of Rio de Janeiro

CNPq – The Brazilian National Council for Scientific and Technological Development

How does our attitude to drugs in general shape our reaction to “smart drugs” in particular? Ruairidh Battleday and Anna-Katharine Brem have recently published a systematic review of 24 studies on the effect of modafinil on healthy individuals. They concluded that “modafinil may well deserve the title of the first well-validated pharmaceutical ‘nootropic’ agent.”[1] This publication has rekindled the debate on the ethics of “smart drugs”. Of course further studies are necessary for a better assessment of the safety and efficacy of modafinil. But if modafinil, or some other drug, proves safe and effective in the future, are there reasons to oppose its widespread use in society?

Continue reading

Less cooperation, please

Written by Joao Fabiano

Since the idea of enhancing human morality was proposed – and perhaps long before then – there has been a great deal of scientific research directly or indirectly inspired by the goal of improving human moral dispositions. Manipulations which result in increased levels of cooperation, prosociality or altruism are often seen as promising discoveries towards the path of developing moral enhancement technologies. The fact that increasing cooperation between individuals would be going in the wrong direction seems to be ignored. The problem moral enhancement proposes to fix is large-scale cooperation – cooperation between groups of individuals – not between individuals inside a group. Issues like global warming and nuclear disarmament arise primarily in the interaction between large groups of individuals, not in the interaction of individuals within the same group.

In actuality, humans already cooperate well inside small groups. We have evolved many emotional and cognitive mechanisms which enable us to function quite satisfactorily in the context of small cooperative groups such as the ones more frequently prominent in pharmacological research. Many have proposed local economies as the ideal design for producing sustainable management of common resources[1]. There is not that much room for improvement there.

On the other hand, when it comes to interactions between groups of different religions, nationalities and morals we can fail spectacularly. What’s more, our ability to cooperate well inside groups seems to be directly correlated with our inability for cooperation between groups. Continue reading

Effort, psychological continuity, human enhancement and superintelligence

One argument against human enhancement is that it is cheating. Cheating others and oneself. One may be cheating oneself for various reasons; because one took the easy path instead of actually acquiring a certain capacity, because once one enhances one is no longer oneself, because enhancements are superficial among others. I would like to try to develop further the intuition that “it is not the same person any more”. I will concentrate in forms of enhancement that involve less effort, are considered easier, or faster than conventional means because the cheating argument seems directed at them. In fact, most forms of non-conventional technological enhancements being proposed seem to be easier routes towards self-improvement. I will also explore how my considerations might mean trouble for any type of disruptive technology besides radical human enhancement, such as superintelligence or whole-brain emulation. Continue reading


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