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Is it ever OK for scientists to experiment on themselves?

Jonathan Pugh, University of Oxford; Dominic Wilkinson, University of Oxford, and Julian Savulescu, University of Oxford This article is republished from The Conversation under a Creative Commons license. Read the original article. A virologist named Beata Halassy recently made headlines after publishing a report of successfully treating her own breast cancer by self-administering an experimental… Read More »Is it ever OK for scientists to experiment on themselves?

Declaration of Helsinki turns 60 – how this foundational document of medical ethics has stood the test of time

The declaration of Helsinki recently turned 60, but don’t feel bad if you missed the celebrations. It probably passed unnoticed by most people not working in the medical field – and possibly even a good few in the field. If you’re not familiar with the declaration – adopted by the World Medical Association on October… Read More »Declaration of Helsinki turns 60 – how this foundational document of medical ethics has stood the test of time

Why a US State Court Ruling on the Rights of Children Before Birth is Unjust

Dominic Wilkinson, University of Oxford. In 2020, in a medical facility in one of the southern states of the US, a patient wandered into an unsecured nursery for extremely premature children. Unfortunately, the patient managed to accidentally disconnect multiple babies from their life support. Worried that they would get in trouble, they fled the scene.… Read More »Why a US State Court Ruling on the Rights of Children Before Birth is Unjust

Cross Post: What’s wrong with lying to a chatbot?

Written by Dominic Wilkinson, Consultant Neonatologist and Professor of Ethics, University of Oxford

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Imagine that you are on the waiting list for a non-urgent operation. You were seen in the clinic some months ago, but still don’t have a date for the procedure. It is extremely frustrating, but it seems that you will just have to wait.

However, the hospital surgical team has just got in contact via a chatbot. The chatbot asks some screening questions about whether your symptoms have worsened since you were last seen, and whether they are stopping you from sleeping, working, or doing your everyday activities.

Your symptoms are much the same, but part of you wonders if you should answer yes. After all, perhaps that will get you bumped up the list, or at least able to speak to someone. And anyway, it’s not as if this is a real person.Read More »Cross Post: What’s wrong with lying to a chatbot?

Cross Post: Should A Health Professional Be Disciplined For Reporting An Illegal Abortion?

Written by: Prof Dominic Wilkinson, University of Oxford

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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There have been several high-profile cases in the last year of women in the UK being prosecuted for allegedly obtaining abortions illegally. In 2022, there were 29 cases of suspected unlawful abortions that were reported to police – almost a twofold rise on the number reported four years earlier.

In response to this, the Royal College of Obstetrics and Gynaecologists (RCOG) has issued guidance that seeks to clarify the legal obligations of healthcare professionals. The full guideline has not yet been released, but the RCOG insists that professionals “are under no legal obligation to contact the police following an abortion, pregnancy loss or unattended delivery”.Read More »Cross Post: Should A Health Professional Be Disciplined For Reporting An Illegal Abortion?

Cross Post: Dutch Government to Expand Euthanasia Law to Include Children Aged One to 12 – An Ethicist’s View

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Written by Dominic Wilkinson, University of Oxford

Ernst Kuipers, the Dutch health minister, recently announced that regulations were being modified to allow doctors to actively end the lives of children aged one to 12 years who were terminally ill and suffering unbearably.

Previously, assisted dying was an option in the Netherlands in rare cases in younger children (under one year) and in some older teenagers who requested voluntary euthanasia. Until now, Belgium was the only country in the world to allow assisted dying in children under 12.

Under the proposal, it will remain against the law for doctors in the Netherlands to actively end the life of a child under the age of 12. However, a force majeure clause gives prosecutors the discretion not to prosecute in exceptional circumstances.

In 2005, Dutch doctors and legal experts published guidelines (the so-called “Groningen protocol”) elaborating when these exceptional circumstances would apply for infants under the age of one year. That included certainty about diagnosis and prognosis, “hopeless and unbearable suffering”, the support of both parents and appropriateness confirmed by an independent doctor.

The new regulations would allow the same principles to apply to children between one and 12 years of age.Read More »Cross Post: Dutch Government to Expand Euthanasia Law to Include Children Aged One to 12 – An Ethicist’s View

Cross Post: Why Government Budgets are Exercises in Distributing Life and Death as Much as Fiscal Calculations

Written by Hazem Zohny, University of Oxford

Sacrificial dilemmas are popular among philosophers. Should you divert a train from five people strapped to the tracks to a side-track with only one person strapped to it? What if that one person were a renowned cancer researcher? What if there were only a 70% chance the five people would die?

These questions sound like they have nothing to do with a government budget. These annual events are, after all, conveyed as an endeavour in accounting. They are a chance to show anticipated tax revenues and propose public spending. We are told the name of the game is “fiscal responsibility” and the goal is stimulating “economic growth”. Never do we talk of budgets in terms of sacrificing some lives to save others.

In reality, though, government budgets are a lot like those trains, in philosophical terms. Whether explicitly intended or not, some of us take those trains to better or similar destinations, and some of us will be left strapped to the tracks. That is because the real business of budgets is in distributing death and life. They are exercises in allocating misery and happiness.Read More »Cross Post: Why Government Budgets are Exercises in Distributing Life and Death as Much as Fiscal Calculations

Cross Post: Tech firms are making computer chips with human cells – is it ethical?

Written by Julian Savulescu, Chris Gyngell, Tsutomu Sawai
Cross-posted with The Conversation

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Julian Savulescu, University of Oxford; Christopher Gyngell, The University of Melbourne, and Tsutomu Sawai, Hiroshima University

The year is 2030 and we are at the world’s largest tech conference, CES in Las Vegas. A crowd is gathered to watch a big tech company unveil its new smartphone. The CEO comes to the stage and announces the Nyooro, containing the most powerful processor ever seen in a phone. The Nyooro can perform an astonishing quintillion operations per second, which is a thousand times faster than smartphone models in 2020. It is also ten times more energy-efficient with a battery that lasts for ten days.

A journalist asks: “What technological advance allowed such huge performance gains?” The chief executive replies: “We created a new biological chip using lab-grown human neurons. These biological chips are better than silicon chips because they can change their internal structure, adapting to a user’s usage pattern and leading to huge gains in efficiency.”

Another journalist asks: “Aren’t there ethical concerns about computers that use human brain matter?”

Although the name and scenario are fictional, this is a question we have to confront now. In December 2021, Melbourne-based Cortical Labs grew groups of neurons (brain cells) that were incorporated into a computer chip. The resulting hybrid chip works because both brains and neurons share a common language: electricity.

Read More »Cross Post: Tech firms are making computer chips with human cells – is it ethical?

Cross Post: Western Pharma Companies Should Supply Only Essential Medicines to Russia

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Written by Alex Polyakov, The University of Melbourne and Julian Savulescu, University of Oxford

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In response to Russia’s invasion of Ukraine and overwhelming destruction of property and loss of innocent lives, a number of western companies – from McDonalds to Apple – stopped or severely limited their activities in the Russian Federation.

One glaring exception appears to be the majority of western pharmaceutical companies that continue to supply medicines and equipment.

There is growing political and consumer pressure on these companies to take steps to join the concerted efforts designed to pressure the
Russian government to stop the war in Ukraine.Read More »Cross Post: Western Pharma Companies Should Supply Only Essential Medicines to Russia

Cross Post: Is This the End of the Road for Vaccine Mandates in Healthcare?

Written by Dominic Wilkinson, Alberto Giubilini, and Julian Savulescu

The UK government recently announced a dramatic U-turn on the COVID vaccine mandate for healthcare workers, originally scheduled to take effect on April 1 2022. Health or social care staff will no longer need to provide proof of vaccination to stay employed. The reason, as health secretary Sajid Javid made clear, is that “it is no longer proportionate”.

There are several reasons why it was the right decision at this point to scrap the mandate. Most notably, omicron causes less severe disease than other coronavirus variants; many healthcare workers have already had the virus (potentially giving them immunity equivalent to the vaccine); vaccines are not as effective at preventing re-infection and transmission of omicron; and less restrictive alternatives are available (such as personal protective equipment and lateral flow testing of staff).Read More »Cross Post: Is This the End of the Road for Vaccine Mandates in Healthcare?