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October 2015

Why are unethical neonatal trials still taking place in developing countries?

By Dominic Wilkinson, @Neonatalethics

Earlier this year, the Lancet published a trial (the ‘ACT’ trial) involving 100,000 babies at risk of being born prematurely in developing countries. Half of the mothers in the ACT trial did not receive a simple cheap medicine that has been previously shown in multiple trials and meta-analysis to reduce the risk of death for premature babies. From the ACT trial results, it appears that 89 additional babies died as a result of their mothers taking part in the trial.

Surely this is an egregious example of unethical research? It appears to be in breach of the World Medical Association Declaration of Helsinki standards. Why did ethics committees allow the research? Why did a major journal like the Lancet publish it? Why aren’t bioethicists and activist and advocacy groups like Public Citizen jumping up and down in outrage?

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Gene editing and eugenics

A study published last week in the journal Cell has led to speculation that a powerful new gene editing technique is about to be developed.

Gene editing has received widespread media coverage over the past few months. Most of the excitement has centred on a specific gene editing technique, the CRISPR-cas9 system. Research conducted with CRISPR-cas9 on human embryos has been highly controversial, at least partly because some people fear it will lead to gene editing being used to alter the human germline for clinical applications, and will have unpredictable effects on future generations.

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Don’t write evil algorithms

Google is said to have dropped the famous “Don’t be evil” slogan. Actually, it is the holding company Alphabet that merely wants employees to “do the right thing”. Regardless of what one thinks about the actual behaviour and ethics of Google, it seems that it got one thing right early on: a recognition that it was moving in a morally charged space.

Google is in many ways an algorithm company: it was founded on PageRank, a clever algorithm for finding relevant web pages, scaled up thanks to MapReduce algorithms, use algorithms for choosing adverts, driving cars and selecting nuances of blue. These algorithms have large real world effects, and the way they function and are used matters morally.

Can we make and use algorithms more ethically?

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Guest Post: What (if anything) makes extinction bad?

Catia Faria, Pompeu Fabra University

Follow Catia on Twitter here

 Throughout history, countless species have come into existence only to later become extinct. Whether extinction is caused by natural processes or human agency, environmental scientists and the general public seem to agree that extinction is a bad thing and that, therefore, conservation efforts should be made to counteract, and perhaps revert, the losses. Resources are often devoted to the reintroduction of endangered species into ecosystems in which they have long been absent. In other cases, states implement measures to protect autochthonous species (that is, species which are native to a certain natural environment, as opposed to introduced as a result of human activity) which are threatened by the presence of a foreign species by eradicating the members of the latter. There are entire organisations dedicated simply to the aim of preventing the extinction of species whose continued existence is at risk.  However, these practices rely on rather controversial assumptions.

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Mandatory submission of patient information about FGM: a pointless, damaging, discriminatory mess

Brenda Kelly and Charles Foster

Female Genital Mutilation (‘FGM’) is a term covering various procedures involving partial or total removal of the external female genitalia or other injury to the female genital organs for non-medical reasons (WHO, 2012). It can be associated with immediate and long-term physical and psychological health problems. FGM is prevalent in Africa, Middle East and South East Asia as well as within diaspora communities from these countries

The Government, keenly aware of the political capital in FGM, has come down hard. The Serious Crime Act 2015 makes it mandatory to report to the police cases of FGM in girls under the age of 18. While we have some issues with that requirement, it is at least concordant with the general law of child protection.

What is of more concern is the requirement, introduced by the cowardly device of a Ministerial Direction and after the most cursory consultation (in which the GMC and the RCOG hardly covered themselves in glory), by which healthcare professionals, from October 2015, are legally obliged to submit patient-identifiable information to the Department of Health (‘DOH’) on every female patient with FGM who presents for whatever reason, through the Enhanced Dataset Collection (EDC). The majority of these women will have undergone FGM in their country of origin prior to coming to the UK.Read More »Mandatory submission of patient information about FGM: a pointless, damaging, discriminatory mess

Some thoughts on reparations

Consider the following case. Imagine you inherit a fortune from your parents. With that money, you buy a luxurious house and you pay to get a good education, which later allows you to find a job where you earn a decent salary. Many years later, you find out that your parents made their fortune through a very bad act—say, defrauding someone. You also find out that the scammed person and his family lived an underprivileged life from that moment on.

What do you think you would need to do to fulfill your moral obligations?

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Rugby and the Love of the Underdog

The Rugby World Cup is now well underway in England and Wales, and rugby fans have possibly already seen one of its most surprising results and entertaining games. On the second day of the tournament, Japan defied the odds to earn a narrow 34-32 victory over South Africa. The result stunned the rugby world – prior to the result, South Africa had been hailed as possible tournament winners, having been already been crowned world cup champions in 1995 and 2007, whilst few outside the Japanese camp gave them a serious chance of success, with bookmakers classing them as 80-1 underdogs. It truly was a victory of Goliath-slaying proportions.

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