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Bioethics

The Non-Rationality of Radical Human Enhancement and Transhumanism

Written by David Lyreskog

 

The human enhancement debate has over the last few decades been concerned with ethical issues in methods for improving the physical, cognitive, or emotive states of individual people, and of the human species as a whole. Arguments in favour of enhancement, particularly from transhumanists, typically defend it as a paradigm of rationality, presenting it as a clear-eyed, logical defence of what we stand to gain from transcending the typical limits of our species.Read More »The Non-Rationality of Radical Human Enhancement and Transhumanism

Nudges and Incomplete Preferences

Written by Sarah Raskoff

(Post is based on my recently published paper in Bioethics) 

Nudges are small changes in the presentation of options that make a predictable impact on people’s decisions. Proponents of nudges often claim that they are justified as paternalistic interventions that respect autonomy: they lead people to make better choices, while still allowing them to choose for themselves. A classic example is changing the location of food items in a cafeteria so that healthier choices are more salient. The salience of healthy foods predictably leads people to select them, even though they are still free to select the unhealthy options, too.

Nudges have become increasingly popular, but there are many objections to their widespread use. Some allege that nudges do not actually benefit people, while others suspect that they do not really respect autonomy. Although there are many ways of making sense of this latter concern, in a recent paper, I develop a new version of this objection, which takes as its starting point the observation that people often have incomplete preferences.Read More »Nudges and Incomplete Preferences

Brain Cells, Slime Mould, and Sentience Semantics

Recent media reports have highlighted a study suggesting that so-called “lab grown brain cells” can “play the video game ‘Pong’”. Whilst the researchers have described the system as ‘sentient’, others have maintained that we should use the term ”thinking system” to describe the system that the researchers created.

Does it matter whether we describe this as a thinking system, or a sentient one?

Read More »Brain Cells, Slime Mould, and Sentience Semantics

Protecting Children or Policing Gender?

Laws on genital mutilation, gender affirmation and cosmetic genital surgery are at odds. The key criteria should be medical necessity and consent.

By Brian D. Earp (@briandavidearp)

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In Ohio, USA, lawmakers are currently considering the Save Adolescents from Experimentation (SAFE) Act that would ban hormones or surgeries for minors who identify as transgender or non-binary. In April this year, Alabama passed similar legislation.

Alleging anti-trans prejudice, opponents of such legislation say these bans will stop trans youth from accessing necessary healthcare, citing guidance from the American Psychiatric Association, the American Medical Association and the American Academy of Pediatrics.

Providers of gender-affirming services point out that puberty-suppressing medications and hormone therapies are considered standard-of-care for trans adolescents who qualify. Neither is administered before puberty, with younger children receiving psychosocial support only. Meanwhile genital surgeries for gender affirmation are rarely performed before age 18.

Nevertheless, proponents of the new laws say they are needed to protect vulnerable minors from understudied medical risks and potentially lifelong bodily harms. Proponents note that irreversible mastectomies are increasingly performed before the age of legal majority.

Republican legislators in several states argue that if a child’s breasts or genitalia are ‘healthy’, there is no medical or ethical justification to use hormones or surgeries to alter those parts of the body.

However, while trans adolescents struggle to access voluntary services and rarely undergo genital surgeries prior to adulthood, non-trans-identifying children in the United States and elsewhere are routinely subjected to medically unnecessary surgeries affecting their healthy sexual anatomy — without opposition from conservative lawmakers.

Read More »Protecting Children or Policing Gender?

The Homeric Power of Advance Directives

By Charles Foster

[Image: Ulysses and the Sirens: John William Waterhouse, 1891: National Gallery of Victoria, Melbourne]

We shouldn’t underestimate Homer’s hold on us. Whether or not we’ve ever read him, he created many of our ruling memes.

I don’t think it’s fanciful (though it might be ambitious) to suggest that he, and the whole heroic ethos, are partly responsible for our uncritical adoption of a model of autonomy which doesn’t do justice to the sort of creatures we really are. That’s a big claim. I can’t justify it here. But one manifestation of that adoption is our exaggerated respect for advance directives – declarations made when one is capacitous about how one would like to be treated if incapacitous, and which are binding if incapacity supervenes if (in English law) the declaration is ‘valid and applicable.’ 1.

I suspect that some of this respect comes from the earliest and most colourful advance directive story ever: Odysseus and the Sirens.Read More »The Homeric Power of Advance Directives

Cross Post: Tech firms are making computer chips with human cells – is it ethical?

Written by Julian Savulescu, Chris Gyngell, Tsutomu Sawai
Cross-posted with The Conversation

Shutterstock

Julian Savulescu, University of Oxford; Christopher Gyngell, The University of Melbourne, and Tsutomu Sawai, Hiroshima University

The year is 2030 and we are at the world’s largest tech conference, CES in Las Vegas. A crowd is gathered to watch a big tech company unveil its new smartphone. The CEO comes to the stage and announces the Nyooro, containing the most powerful processor ever seen in a phone. The Nyooro can perform an astonishing quintillion operations per second, which is a thousand times faster than smartphone models in 2020. It is also ten times more energy-efficient with a battery that lasts for ten days.

A journalist asks: “What technological advance allowed such huge performance gains?” The chief executive replies: “We created a new biological chip using lab-grown human neurons. These biological chips are better than silicon chips because they can change their internal structure, adapting to a user’s usage pattern and leading to huge gains in efficiency.”

Another journalist asks: “Aren’t there ethical concerns about computers that use human brain matter?”

Although the name and scenario are fictional, this is a question we have to confront now. In December 2021, Melbourne-based Cortical Labs grew groups of neurons (brain cells) that were incorporated into a computer chip. The resulting hybrid chip works because both brains and neurons share a common language: electricity.

Read More »Cross Post: Tech firms are making computer chips with human cells – is it ethical?

Exercise, Population Health and Paternalism

Written by Rebecca Brown

 

The NHS is emphatic in its confidence that exercise is highly beneficial for health. From their page on the “Benefits of exercise” come statements like:

“Step right up! It’s the miracle cure we’ve all been waiting for”

“This is no snake oil. Whatever your age, there’s strong scientific evidence that being physically active can help you lead a healthier and happier life”

“Given the overwhelming evidence, it seems obvious that we should all be physically active. It’s essential if you want to live a healthy and fulfilling life into old age”.

Setting aside any queries about the causal direction of the relationship between exercise and good health, or the precise effect size of the benefits exercise offers, it at least seems that the NHS is convinced that it is a remarkably potent health promotion tool.Read More »Exercise, Population Health and Paternalism

The Aliens Are Coming

UFO against the sky. Free public domain CC0 photo

By Charles Foster

It’s said that 2022 is going to be a bumper year for UFO revelations. Secret archives are going to be opened and the skies are going to be probed as never before for signs of extraterrestrial life.

This afternoon we might be presented with irrefutable evidence not just of life beyond the Earth, but of intelligences comparable in power and subtlety to our own. What then? Would it change our view of ourselves and the universe we inhabit? If so, how? Would it change our behaviour? If so how?

Much would depend, no doubt, on what we knew or supposed about the nature and intentions of the alien intelligences. If they seemed hostile, intent on colonising Planet Earth and enslaving us, our reactions would be fairly predictable. But what if the reports simply disclosed the existence of other intelligences, together with the fact that those intelligences knew about and were interested in us?Read More »The Aliens Are Coming

Three Observations about Justifying AI

Written by:  Anantharaman Muralidharan, G Owen Schaefer, Julian Savulescu
Cross-posted with the Journal of Medical Ethics blog

Consider the following kind of medical AI. It consists of 2 parts. The first part consists of a core deep machine learning algorithm. These blackbox algorithms may be more accurate than human judgment or interpretable algorithms, but are notoriously opaque in terms of telling us on what basis the decision was made. The second part consists of an algorithm that generates a post-hoc medical justification for the core algorithm. Algorithms like this are already available for visual classification. When the primary algorithm identifies a given bird as a Western Grebe, the secondary algorithm provides a justification for this decision: “because the bird has a long white neck, pointy yellow beak and red eyes”. The justification goes beyond just a description of the provided image or a definition of the bird in question, and is able to provide a justification that links the information provided in the image to the features that distinguish the bird. The justification is also sufficiently fine grained as to account for why the bird in the picture is not a similar bird like the Laysan Albatross. It is not hard to imagine that such an algorithm would soon be available for medical decisions if not already so. Let us call this type of AI “justifying AI” to distinguish it from algorithms which try, to some degree or other, to wear their inner workings on their sleeves.

Possibly, it might turn out that the medical justification given by the justifying AI sounds like pure nonsense. Rich Caruana et al present a  case whereby asthmatics were deemed less at risk of dying by pneumonia. As a result, it prescribed less aggressive treatments for asthmatics who contracted pneumonia. The key mistake the primary algorithm made was that it failed to account for the fact that asthmatics who contracted pneumonia had better outcomes only because they tended to receive more aggressive treatment in the first place. Even though the algorithm was more accurate on average, it was systematically mistaken about one subgroup. When incidents like these occur, one option here is to disregard the primary AI’s recommendation. The rationale here is that we could hope to do better than by relying on the blackbox alone by intervening in cases where the blackbox gives an implausible recommendation/prediction. The aim of having justifying AI is to make it easier to identify when the primary AI is misfiring. After all, we can expect trained physicians to recognise a good medical justification when they see one and likewise recognise bad justifications. The thought here is that the secondary algorithm generating a bad justification is good evidence that the primary AI has misfired.

The worry here is that our existing medical knowledge is notoriously incomplete in places. It is to be expected that there will be cases where the optimal decision vis a vis patient welfare does not have a plausible medical justification at least based on our current medical knowledge. For instance, Lithium is used as a mood stabilizer but the reason why this works is poorly understood. This means that ignoring the blackbox whenever a plausible justification in terms of our current medical knowledge is unavailable will tend to lead to less optimal decisions. Below are three observations that we might make about this type of justifying AI.

Read More »Three Observations about Justifying AI

Your eyes will be discontinued: what are the long-term responsibilities for implants?

by Anders Sandberg

What do you do when your bionic eyes suddenly become unsupported and you go blind again? Eliza Strickland and Mark Harris have an excellent article in IEEE Spectrum about the problems caused when the bionics company Second Sight got into economic trouble. Patients with their Argus II eyes found that upgrades could not be made and broken devices not replaced. What kind of  responsibility does a company have for the continued function of devices that become part of people?

Read More »Your eyes will be discontinued: what are the long-term responsibilities for implants?