Preventing Polka-Dot Problems: Should Measles Vaccination be Compulsory?

by Anders Sandberg
May 23, 2008

Jim Todd reports about his measles experience at BBC News. A number of years back such a report about how a case of adult measles feels would have been absurd, since so many had suffered it. A few years back it would have been absurd because measles was rare thanks to vaccination. But now, due to a reduction in vaccinations, the risk of measles is rising. Health chiefs in London are stepping up the vaccination program to try to stave off the rising number of cases. The key problem is that in many areas of London only 62% of toddlers
have been immunised, compared to the 95% that is needed to achieve herd immunity.
Vaccinated people act as firebreaks: if enough people are immune to a
disease long chains of infection become improbable, and epidemics do
not occur. Given this, should measles vaccination be compulsory?

Brain Boosting and Cheating in Exams: Four Responses

by Practical Ethics
May 22, 2008

A report by the Academy of Medical Sciences looking at different aspects of drug use and mental health has identified a growing trend for off-label use of drugs intended for the treatment of diseases including narcolepsy, ADHD and Alzheimer’s. The use of such drugs by a healthy individual can improve memory, alertness and concentration. While the report does not condemn the practice, it raises a number of potential concerns over safety, and fairness. Professor Les Iversen, report co-author, highlighted concerns that the use of enhancement in exams would unfairly advantage wealthier students, and suggested that the use of such drugs could be considered cheating. The report recommends that legislation is prepared to tackle the misuse of such drugs, including the potential for urine testing in schools and universities.

Below are responses from Julian Savulescu, Nick Bostrom, Anders Sandberg and Mark Sheehan on the effects of cognitive enhancing drugs, and the issue of cheating

HFEA and Regulating Reproduction:Triumph for Rationality and Victory for Secular Ethics

by Julian Savulescu
May 22, 2008

MPs voted on Tuesday on two of the most controversial issues surrounding reproduction- the provision of IVF treatment, and the availability of legal abortion. Under the new laws, IVF clinics will no longer have a legal requirement to consider the need for a father, but will instead be asked to ensure provision of ‘supportive parenting’, removing any barrier to single women and lesbian couples conceiving through the treatment. In a separate amendment, MPs were asked to consider the legal time limit on abortion, which currently stands at 24 weeks. Given the option to reduce this limit to 22, 20 or even just 12 weeks, MPs voted by a comfortable majority to stick with the status quo.

The UK is now at the forefront of rational reform to legislation governing reproduction and research. The Human Fertilisation and Embryology Bill has now approved the creation of human admixed embryos, with important implications for scientific advance.

Blog on Admixed Embryos
Savulescu, J., The Case for Creating Human -Non Human Cell Lines, Bioethics Forum
Human Enhancement papers, media and other resources for free download

It has also reformed the regulation of reproduction in a thoroughly sensible manner.

The new asbestos?

by Toby Ord
May 21, 2008

Carbon nanotubes are tiny man-made fibers with an incredibly high tensile strength. They are one of the most promising nanotechnological developments with many potential applications in electronics, medicine and futuristic materials. However, a new study by a group of scientists from the US and the UK suggests that carbon nanotubes may cause health problems similar to those of asbestos. The problem comes from their similar shapes: both nanotubes and asbestos consist of hard microscopic fibers that can cause significant damage to the lining of the lungs. The study involved exposing mice to nanotubes and found that nanotubes of a certain size caused asbestos-like inflammations and lesions.

The New Law on Admixed Embryos and the Genetic Heritage of the Living Kingdom

by Julian Savulescu
May 21, 2008

Scientists in the US recently created a fluorescent human embryo. This was achieved by inserting a gene for green fluorescent protein. This shows that it is possible to successfully transfer a gene from a non-human animal to a human and for that gene to express its function. Other animal studies have shown that such gene transfer is both safe and effective, creating super animals, such as mice with colour-vision derived from human genes transferred.

Saviour Siblings Saved!

by Mark Sheehan
May 20, 2008

Two attempts to amend the Human Fertilisation and Embryology Bill’s provision to allow ‘saviour siblings’ failed in the House of Commons yesterday. The first attempt was to block the practice and failed 342 to 163. The second attempt was to limit the provision to life-threatening cases. It was defeated 318 to 149. As it stands the Bill allows embryo testing and hence selection for ‘saviour siblings’ provided that “there is a significant risk that a person [the sibling ‘to be saved’] … will have or develop a serious physical or mental disability, serious illness or any other serious medical condition.”

Viability and the abortion debate – what really matters?

by Dominic Wilkinson
May 19, 2008

MPs in the House of Commons will debate tomorrow whether the cut-off for legal abortions in the UK should be reduced. Currently abortions are permitted up to the 24th week of a pregnancy, and some MPs have argued that this should be reduced to 20 weeks or below. Advocates and opponents of the change have pointed to scientific evidence about the viability of infants born extremely prematurely at 22, 23 and 24 weeks. They seem to believe that if we can answer the scientific question of whether such infants are viable, that will resolve the question about whether or not abortion is permissible at that stage.
That might be the case if there were a consensus on what viability means, and why it is important in questions about abortion time-limits. But, as this article will highlight, there is no such consensus, and it is not straightforward why viability should matter. So far in this public debate there has been little or no mention of the important questions – what is viability, and why is it important in abortion law?

Humane Evolution

by Anders Sandberg
May 19, 2008

Professor John Harris wonders Who’s afraid
of a synthetic human? in the Times. He argues we should support
the Human Fertilisation and Embryology Bill because it will help us develop
effective therapies and enhance ourselves. Science is about bettering our lot,
after all. In particular, he says, synthetic biology may help us avoid going
extinct due to our vulnerabilities and instead enable us to choose (or become)
our successors as a species.

Many people become confused by the
possibility of a posthuman future. The traditional view of the future is a
stark one: either humanity extinct, or humans roughly as they are today. The
posthuman options would be that we either change ourselves so radically that
the resulting species is so fundamentally different from humanity that we
would regard it as something entirely new, or that we create some kind of independent
beings that continue our culture even as traditional humanity retires from the
forefront (hopefully as proud parents of the new beings). The range of possible
options within these scenarios is endless, inviting equally endless and loud
speculation. That tends to distract from the key message of Harris’ essay: we
are leaving the realm of natural evolution and entering what he calls a realm
of enhancement evolution.

The Ethics of ‘Human Admixed Embryos’: Concerns and Responses

by Julian Savulescu
May 19, 2008

By Loane Skene, Professor of Law, University of Melbourne and Julian Savulescu, Uehiro Chair in Practical Ethics and Director Uehiro Centre for Practical Ethics, University of Oxford

The Human Fertilisation and Embryology Authority (HFEA) Bill, currently before the UK Parliament, will, if passed, permit HFEA to license the creation for research of embryos that combine human and animal genetic material (called, in the Bill, ‘human admixed embryos’). These embryos include cybrids which are formed by inserting the nucleus of a human body cell into an animal egg that has had its nucleus removed. Cybrids would produce embryonic stem cells that are 99.9% human. The Bill would also permit other types of embryos to be formed from human and animal genetic material that would be up to half animal. This post explains why scientists want to create human admixed embryos. It then outlines some ethical concerns about the creation of these embryos and responses that may be made to those concerns.

A Second Human Singularity?

by Rebecca Roache, Royal Holloway University of London
May 16, 2008

New Scientist
reports this week claims that the reason human cognitive powers are so
superior to those of other animals has to do not with biology alone, but also
with our ability to interact with others and with the world.