Skip to content

Our Obligations to the Poor

Our Obligations to the Poor

The relationship between the rich and the poor countries of the world has been questioned in a number of ways today. Oxfam have released a report, Investing for Life, which suggests that pharmaceutical companies are missing an important opportunity by not focussing their attention on the large health problems of the poorest countries. At the same time, in the US, apparently significant developments have been made in the production of drought–resistant crops and, in the UK, the government’s chief scientific adviser will call for a rethink on GM crops.

These two issues pull in interestingly different ways. In the first case, the challenging question is how best to balance the value of a market-based research industry with the need to provide assistance to the poorest countries. In the second, the challenge is the price we are prepared to pay for our worries about genetically modified crops. In both cases our obligations to the poor sheds important light on the values of our society.

Read More »Our Obligations to the Poor

The importance of life extension

One of the most important ideas in public health is that we can never really save lives: we just extend them. If a doctor ‘saves the life’ of a 60 year old patient who later dies at 90 years of age, then she hasn’t actually stopped the patient dying, but has extended the patient’s life by 30 years.

With this in mind, consider the recent research by a team from the Howard Hughes Medical Institute. They investigated the effects of a vast array of different chemicals on a test organism, the tiny nematode worm C. elegans. While many were found to be harmful, one chemical was greatly beneficial, significantly extending the worm’s short life span.

Read More »The importance of life extension

Is this the end of the debate for human embryo research?

Two landmark papers published this week have demonstrated that stem cells (“Induced Pluripotent Stem Cells”) capable of developing into a wide range of different tissues can be made from human skin cells. It has been claimed in some quarters that this breakthrough will end the debate about the use of embryonic stem cells.

This news comes fast on the heels of the successful generation of stem cells from cloned monkey embryos, discussed in this blog last week (see also Raffaela Hillerbrand’s post), and was anticipated in the weekend papers by the news that a pioneer in cloning research had decided to move his research efforts into the same work on “induced pluripotent cells”.

But is this discovery really likely to end the ethical debate about research using human embryos?

Read More »Is this the end of the debate for human embryo research?

It is 10 O’clock, do you know what your cells are?

BBC File On 4 recently learned that “millions of pounds
of charity donations and taxpayers’ money have been wasted on worthless cancer
studies”. Labs have been using contaminated cell lines – rather than
experimenting on the cancer cells they thought they had researchers have been
studying other kinds of cancers or even mice cells. Perhaps the most remarkable (and newsworthy)
aspect of the whole affair is that it is not a recent surprise: researchers
sounded the alarm bell – repeatedly – in the early 1970’s. Science noted in
1974 that “a lot of people may have been spending a lot of time and money on
misguided research.” That was 33 years ago, a millennium of time in cell
biology.

Read More »It is 10 O’clock, do you know what your cells are?

Imaging the Political Brain

In an interesting study published in the Journal of Cognitive Neuroscience in 2006 but widely circulated earlier, Drew Westen and his colleagues at Emory University used fMRI to image the brains of committed Democrats and Republicans before the 2004 Presidential election. Although the subject matter was topical, the aim of the study was not to… Read More »Imaging the Political Brain

Lie-detection using functional MRI

Scientific American last week reported that psychiatrist Sean Spence and collaborators at the University of Sheffield are developing a lie-detection test based on functional magnetic resonance imaging (fMRI) technology. Using fMRI, Spence and colleagues are able to monitor blood flow to certain areas of the brain’s prefrontal cortex that are implicated in the regulation of… Read More »Lie-detection using functional MRI

Good drug, bad drug?

News The Lancet has published two articles on the efficacy and safety of the anti-obesity drug Acomplia.  This has been widely reported in the news as showing that patients using the drug have well over double the risk of depression and anxiety.  This comes on top of US studies linking Acomplia to suicidal thoughts. Commentary… Read More »Good drug, bad drug?