“Electroceuticals”, or therapies utilising electricity, are nothing new and range from the widely accepted defibrillator/ pace makers to the more controversial electric shock therapies like ECT sometimes employed to treat severe depression.
But a recent article in Nature argues that these are just a small, crude sample of what electroceuticals may be able to offer in the future. Universities and pharmaceutical companies are researching a wide range of therapies based around electrical stimulation, promising benefits (in the long term) as diverse as mind-controlled prosthetic limbs to a treatment for anorexia. Transcranial Electric Stimulation (TES) is delivering some promising results in depression and treatment of learning disabilities.
Not only is the research potential there, but it appears that the funding is too. Nature report that GlaxoSmithKline are funding 40 researchers to pursue research in this area, amongst other initiatives to kick start electroceutical development. And earlier this year, the US invested $110 million from 2014’s budget for the “Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative”. At the same time, over in Europe, work has commenced on a 10 year, billion pound ‘Human Brain Project, bringing together 135 institutions to try to map parts of the human brain via computer simulations.
We may be starting out on the track for the “holy grail” of neuroscience: strategic control of single neuronal activity. This is, apparently, one of GSK’s goals.
With that level of control, we could finally reach the realms of science fiction: where the mind and therefore the person is under external control. Freedom might be annihilated.
We would face confronting questions over authenticity and identity. There would be alienation between the pre-existing person and their subsequent brain activity.
Burgess’ A Clockwork Orange is a graphic illustration of a common objection to enhancement, the erosion of freedom. TES at present does not appear to represent a major threat to freedom, but it is one of a family of technologies that could one day be used for effective mind control.
A recent study has shown that a person’s implicit racial bias can be reduced if she spends some time experiencing her body as dark-skinned. Psychologists in Spain used an immersive virtual reality technique to allow participants to ‘see’ themselves with a different skin colour. They measured the participants’ implicit racial bias before and after the intervention, finding that the embodiment of light-skinned individuals in a dark-skinned virtual body at least temporarily reduced their implicit bias against people who are coded as ‘out-group’ on the basis of skin colour.
Implicit racial bias is an evolved, unconscious tendency to feel more positively towards members of one’s own race (one’s ‘in-group’) than towards members of a different race (members of an ‘out-group’). The bias can be (and was in this study) measured using a version of the implicit association test, which requires participants to quickly catagorise faces (black or white) and words (positive or negative) into groups. Implicit bias is calculated from the differences in speed and accuracy between categorising (white faces, positive words) and (black faces, negative words) compared to (black faces, positive words) and (white faces, negative words). Crucially, implicit racial bias has been shown to be uncorrelated with explicit racial bias – self-reports of negative racial stereotypes. This means that even those who are not consciously averse to people from other racial groups often demonstrate a deep-seated bias against them as an evolutionary hangover. Hearteningly, the authors of the study started from the idea that encoding people by race may be a reversible by-product of human evolution used to detect coalitional alliances. What their study confirmed is that immersive virtual reality provides a powerful tool for placing people into a different race ‘coalition’ by changing their body representation and consequently reducing their implicit aversion to the racial characteristics there represented. Continue reading
Pharmaceutical treatment of attention deficit-hyperactivity disorder (ADHD) is associated with reduced criminality according to a study published yesterday in the New England Journal of Medicine. The study of over 25,000 Swedish adults with the disorder found that men undergoing pharmaceutical treatments had a 51% chance of committing at least one crime in a 4-year period compared to 63% for those not in treatment. The risk of criminality for women with ADHD was 25% for those taking medication, and 31% for those not in treatment. It’s possible, of course, that the reduction in criminality associated with treatment was due not to the treatment itself, but to other factors, such as desire to improve behaviour, which could have both motivated treatment and reduced criminality. However, even when the investigators adjusted for likely confounders, they found that treatment was associated with significantly reduced criminal offending. Thus, their findings are at least suggestive of a causal relationship between medication and reduced crime.
It will be interesting to see how such a relationship, if it can be further supported, will be viewed by the general public and medical profession. Will it be seen as strengthening or weakening the case for ADHD treatment?
‘I was always the life and soul of the party, flirting with everyone’, wrote Lucille Howe, in ‘Fabulous Magazine’, (22 July 2012), ‘but I wanted John to fall in love with the real, quieter me’. In the same article, Charlotte Ruhle notes how her psychotherapy helped her to recover from a broken relationship. ‘[My] friends started saying I….seemed more like my old self.‘
The media, and indeed our ordinary conversations, are awash with this sort of language. Not only are we conscious – having a sense that there is an ‘I’ that is in some sort of continuity with the ‘I’ that existed yesterday, will hopefully exist tomorrow, and to whom things happen – but we have firm convictions about the nature of the ‘I’. When it is not allowed to express itself – to ‘be itself’, we complain. Depending on our education, we say that we’re ‘out of sorts’, ‘not myself’, or ‘ontologically vertiginous’. Continue reading
An article in the Israeli newspaper Haaretz reports on the (alleged) frequent use of psychiatric drugs within the Haredi community, at the request of the religious leaders, in order to help members conform with religious norms. Haredi Judaism is the most conservative form of Orthodox Judaism. It is sometimes referred to by outsiders as ultra-Orthodox. Haredim typically live in communities that have limited contact with the outside world. Their lives revolve around Torah study, prayer and family.
In December 2011, the Israel Psychiatric Association held a symposium entitled “The Haredi Community as a Consumer of Mental-Health Services”. One of the speakers was Professor Omer Bonne, director of the psychiatry department at Hadassah University Hospital. Professor Bonne is claimed to have said that sometimes yeshiva students (yeshiva is a religious school) and married men should be given antidepressants even if they do not suffer from depression, because these drugs also suppress sex drive.