Scientists have made a new strain of bird flu that most likely could spread between humans, triggering a pandemic if it were released. A misguided project, or a good idea? How should we handle dual use research where merely knowing something can be risky, yet this information can be relevant for reducing other risks?
Read More »Ferretting out fearsome flu: should we make pandemic bird flu viruses?
X, a patient with reliably diagnosed PVS, lies in a hospital bed for years, fed via a nasogastric tube. He has not, and by definition never will have, any capacity for pain, pleasure or any sort of sensation. Devoted family members come each day to sit by his bedside, but he has no idea that they are devoted, or that they exist.
It is expensive to keep him alive. He occupies a bed and consumes a good deal of nursing time.
The NHS Trust responsible for his care has a limited budget. It decides that the money spent on maintaining his merely biological life would be better spent on dialysis machines. It can, and does, justify its decision in purely utilitarian terms. It writes in the minutes of the relevant committee meeting: ‘For the money we spend keeping X alive, we can save the lives of 10 kidney patients, each of whom will have a good quality of life for many years. The QALY arithmetic makes X’s continued existence nonsensical.’Read More »The cost of living and the cost of dying
By Charles Foster
Three years ago Ana Mejia bore a son, Bryan Santana. To her surprise he had no arms and only one leg. I should have been warned about this, she recently told a Florida court. It was negligent not to warn me. Had I been warned, I would have had an abortion. She asked the court for $9 million compensation. The jury gave her $4.5 million.
The disability rights lobby is predictably outraged. Why, they say, should it be presumed (as it clearly is), that a disabled person’s life isn’t worth living?
If that is Ana Mejia’s presumption, then (at least in relation to a child as relatively mildly disabled as Bryan) it is plainly reprehensible. I don’t know her motivation, but I doubt that she saw it that way. Many parents in her situation (and this is a very common issue in medico-legal practice) don’t make their decisions on the basis of their child’s quality of life at all. A much commoner thought is: ‘A disabled child will disrupt my own life. One of the purposes of pre-natal screening is to enable me to decline to bring into the world a child who does not fit with my ideas about how I should be living my life.’ I will call this thought the ‘pre-natal screening default thought’ (PNSD).Read More »Is a child a blessing?
Last week, the Academy of Medical Sciences released a report calling for better regulation of experiments involving animals containing human tissues or genes. One specific claim made by the report is that experiments which entail “modifying non-human primates to create human-like awareness or behaviour” should be banned. Was it right to call for such a ban?Read More »Creating Non-Human People
The hot new performance-enhancing drug is…beetroot juice!? (original paper)
Nitrates in food reduces the oxygen cost of some forms of exercise and improves high-intensity exercise tolerance. So the researchers gave half a litre of beetroot juice (which is rich in nitrate) or a nitrate depleted placebo to club-level competitive cyclists. The nitrate juice produced better cycling performance when compared to the placebo. On a 16.1 km race beet juice reduced the total time by 2.7% – not much, but presumably enough to matter in a competition.
In any case, this is fun for doping discussions. Should we ban athletes from quaffing beet juice?
Coming to a mini-mart near you. The FDA has just approved nine very grisly looking warning labels—to be slapped on cigarette packs throughout the USA. But will they work to cut smoking … or will they backfire?
Here are some of the top reasons why these labels may not only fail to achieve the FDA’s desired outcome, but could actually do the opposite – leading to more smoking, not less.Read More »Shocking behavior: Government scare tactics, smoking, and public health
By Charles Foster
It was reported this week that 56 year old Eva Ottosson is planning to give her 25 year old daughter, Sara, the uterus in which Sara herself gestated. Sara suffers from Mayer Rokitanksy Kustner Hauser Syndrome: she was born without a uterus.
Predictably the newspapers loved it. And, equally predictably, clever people from the world’s great universities queued up to be eloquently wise about the ethics of the proposal.
But if ethics are concerned with what we should do, there was really nothing worthwhile to be said about Eva Ottosson’s altruism (bar the usual uninteresting caveats about dangerousness and resource allocation), except: ‘Fantastic’.Read More »Uterine transplants: applaud, and then shut up
In book 4 of Homer’s Odyssey, Odysseus’s son Telemachos arrives in Sparta to quiz Menelaos on whether Odysseus is still alive and if so where he might be. Menelaos reduces everyone (including himself) to tears by telling everyone how sad he is that Odysseus hasn’t made it home. He then says it’s time for them… Read More »Good Grief?
Matthew L Baum
Round 1: Baltimore
I first heard of the Malleus Maleficarum, or The Hammer of Witches, last year when I visited Johns Hopkins Medical School in Baltimore, MD, USA. A doctor for whom I have great respect introduced me to the dark leather-bound tome, which he pulled off of his bookshelf. Apparently, this aptly named book was used back in the day (published mid-1400s) by witch-hunters as a diagnostic manual of sorts to identify witches. Because all the witch-hunters used the same criteria as outlined in The Hammer to tell who was a witch, they all –more or less- identified the same people as witches. Consequently the cities, towns, and villages all enjoyed a time of highly precise witch wrangling. This was fine and good until people realized that there was a staggering problem with the validity of these diagnoses. Textbook examples (or Hammer-book examples) these unfortunates may have been, but veritable wielders of the dark arts they were not. The markers of witchcraft these hunters agreed upon, though precise and reliable, simply were not valid.
Read More »Predictors of Alzheimer’s vs. the Hammer of Witches
