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Ethics

The Transplant Case in Real Life

Philosophers have long debated about the moral permissibility of Transplant Cases such as the following one presented by Philippa Foot:

A brilliant transplant surgeon has five patients, each in need of a different organ, each of whom will die without that organ. Unfortunately, there are no organs available to perform any of these five transplant operations. A healthy young traveler, just passing through the city the doctor works in, comes in for a routine checkup. In the course of doing the checkup, the doctor discovers that his organs are compatible with all five of his dying patients. Suppose further that if the young man were to disappear, no-one would suspect the doctor.

Most people believe that it is not permissible for the doctor to murder this patient and harvest his organs, although a few consequentialists, e.g. Alastair Norcross, have argued that it might be acceptable under certain circumstances.

In a possible real-life version of the Transplant Case, the New York Times reported recently that Dr. Hootan C. Roozrokh, a transplant surgeon from Stanford, is being charged with ordering the removal of a life-supporting ventilator and prescribing excessive and improper doses of drugs, apparently in an attempt to hasten the death of a disabled and brain damaged man named Ruben Navarro in order to retrieve his organs sooner. 

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Changing the Building Blocks of Life: Playing God and Being gods

All life on earth has the same simple basic structure. It is based on the genetic code contained in DNA. The differences in DNA between a toad and Albert Einstein are what determines their different properties.

The active ingredients in DNA are also simple. They are 4 bases: cytosine, guanine, adenine and thymine, or A, T, C and G. The order of these 4 bases is what determines the characteristics of life, the differences between Einstein and a toad.

Scientists in California have created two new bases in addition to A, T, C and G: dSICS and DMMO2. These new bases function like natural ones, they pair appropriately with their partner and are faithfully copied by the natural enzyme, DNA polymerase, responsible for making the billions of copies of DNA necessary to programme each cell in the body of a living organism.

At present, these new bases or building blocks do not do anything. But scientists hope they could be used

"for hundreds of purposes: for example, to build complex shapes, to build complex nanostructures, silence disease genes or even perform calculations… [and even]expand the genetic code and ‘evolvability’ of an organism."

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Post-mortem punishment and public dissection.

A television report aired in the US last week claimed that bodies used
in public anatomical exhibitions might have included executed Chinese
prisoners. There have been subsequent denials from exhibitors that any
of the bodies currently being shown in Pittsburgh came from prisoners.
Apparently one exhibition includes bodies of individuals who died from
natural causes but were ‘unclaimed’, while another exhibition includes
only individuals who have consented to their bodies being used for
education or research. But it is interesting to try to ‘dissect’ the
outcry.

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The Rogue Senator and the Protection of Genetic Information

The editors of Nature have today called for the US Senate to bypass Senator Tom Coburn’s (Republican, Oklahoma ) ‘hold’ the Genetic Information Non-discrimination Bill. The Bill, if enacted “would protect people from being discriminated against by health insurers or employers on the basis of their genetic information” but Senator Coburn has used a procedural manoeuvre called a “hold” to prevent it from coming to a vote in the Senate. In their editorial the editors suggest that by putting a hold on this Bill, the senator from Oklahoma is preventing the enormous research and clinical progress from continuing and further developing the era of personalised medicine.

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Earache for teenagers

The BBC today
reported calls to scrap an acoustic device designed to disperse crowds of
troublesome teenagers. There are 3,500
such ‘Mosquito’ devices in use in England, which work by emitting a
sound normally audible only to those under the age of 25. The sound is turned on for 20 seconds at a
time, and becomes irritating after around 15 seconds, causing those who can
hear it to move away. Typically, the
devices are installed in areas where groups of teenagers gather, such as
shopping precincts.

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A child of many parents: a new way to have two mothers

The Guardian and Telegraph, are today reporting that British scientists have created ten human embryos which each include DNA from one man and two women. This was done by taking a one day old IVF embryo and removing its pronuclei (the parts containing the chromosomes from the parents). These were then inserted into an egg cell from the second woman, which has had its nucleus removed. The result is a new embryo with its primary DNA coming from a man and a woman, and the body of its cell coming from the second woman. This is an amazing experiment, and comes hot on the heels of other multi-parent experiments, but why has it been performed and what are the ethical implications?

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Meet Mom, Mom and Mom: is there anything wrong with same-sex genetic parents?

The Daily Mail reports on a New Scientist article about the possibilities of same-sex reproduction. Researchers at Newcastle upon Tyne have coaxed stem cells in male bone marrow to developing  into spermatogonia, which in turn have been coaxed to divide into sperm cells. According to New Scientist they may have succeeded in producing spermatogonia from female marrow, and are now working on the final step to turn them into sperm. In that case it would be possible for two women to be the genetic parents of a child. Other research aims at turning skin cells into eggs, which could allow two males to be genetic parents of a child (with the help of a surrogate mother). While the research aims at helping infertility the obvious possibility is same-sex parenthood. Is it a good idea to create kids with two or three moms, or two dads and a mom?

Read More »Meet Mom, Mom and Mom: is there anything wrong with same-sex genetic parents?

Hybrid Embryos and Dying Children

The BBC yesterday reported that the government is looking into calls to remove the ban on creating human-animal hybrid embryos using cells from dying children. As things stand the Human Fertilisation and Embryology (HFE) Bill being considered in parliament would forbid such research without the consent of the child. In a letter to health minister Lord Darzi, a group led by the Genetic Interest Group (GIG) has argued that the Bill as it stands “imposes a barrier to one of the most potent tools for research into the most severe childhood diseases.” Our understanding of diseases such as Tay Sachs and Spinal Muscular Atrophy stands to be greatly enhanced by the use of stem cells obtained from such hybrid embryos.

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The bread of life: should we enhance our food?

A new study from the US suggests that folic acid supplements may
substantially reduce the risk of premature birth. This has reinforced
calls for the fortification of flour with folic acid. Although this
reported effect on preterm births is new, there are well documented
public health benefits of folic acid.(1) The food standards agency in
the UK finally decided in May last year that folic acid would be added
to either flour or bread, after years of lobbying.

Supplementing bread and flour is an effective way of providing health
supplements on a population level. But how much should we add to food
staples in the name of public health? Should additives be limited to
those that prevent serious disease, or if available, should we add
things to food that enhance health?

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Funding cuts for homoeopathy

The Guardian, Times and BBC are today reporting that National Heath Service funding for homoeopathy is on the decline. A survey conducted by Pulse has found that only 37% percent of the UK’s primary care trusts are still funding homoeopathy services, with more than 25% having reduced funding to homoeopathy in the last two years.

The real news, I would argue, is that more than a third of the UK’s funding bodies are still funding the alternative medicine.

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