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Biotechnology

Announcement: “Brave New Love” in AJOB:Neuroscience – peer commentaries due October 7

Announcement: “Brave New Love” – peer commentaries due October 7 Dear Practical Ethics readers, The paper, “Brave new love: the threat of high-tech ‘conversion’ therapy and the bio-oppression of sexual minorities” by Brian D. Earp, Anders Sandberg, and Julian Savulescu has been accepted for publication in the American Journal of Bioethics: Neuroscience. Proposals for open peer commentaries are… Read More »Announcement: “Brave New Love” in AJOB:Neuroscience – peer commentaries due October 7

Enhanced punishment: can technology make life sentences longer?

by Rebecca Roache

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Edit 26th March 2014: It’s been pointed out to me by various people that this blog post does not make adequately clear that I don’t advocate the punishment methods described here. For a clarification of my views on the subject, please go here. For a Q&A, see here.

Today, the mother and stepfather of Daniel Pelka each received a life sentence for his murder. Daniel was four when he died in March last year. In the last few months of his short life, he was beaten, starved, held under water until he lost consciousness so that his mother could enjoy some ‘quiet time’, denied medical treatment, locked in a tiny room containing only a mattress on which he was expected both to sleep and defecate, humiliated and denied affection, and subjected to grotesquely creative abuse such as being force-fed salt when he asked for a drink of water. His young sibling, who secretly tried to feed and comfort Daniel, was forced to witness much of this; and neighbours reported hearing Daniel’s screams at night.

Daniel’s mother, Magdelena Luczak, and stepfather, Mariusz Krezolek, will each serve a minimum of thirty years in prison. This is the most severe punishment available in the current UK legal system. Even so, in a case like this, it seems almost laughably inadequate. The conditions in which Luczak and Krezolek will spend the next thirty years must, by law, meet certain standards. They will, for example, be fed and watered, housed in clean cells, allowed access to a toilet and washing facilities, allowed out of their cells for exercise and recreation, allowed access to medical treatment, and allowed access to a complaints procedure through which they can seek justice if those responsible for their care treat them cruelly or sadistically or fail to meet the basic needs to which they are entitled. All of these things were denied to Daniel. Further, after thirty years—when Luczak is 57 and Krezolek 64—they will have their freedom returned to them. Compared to the brutality they inflicted on vulnerable and defenceless Daniel, this all seems like a walk in the park. What can be done about this? How can we ensure that those who commit crimes of this magnitude are sufficiently punished?Read More »Enhanced punishment: can technology make life sentences longer?

Enhancement: Rat Race or Supermarket? (Podcasts)

In this special Enhancement seminar, visiting speakers Rob Sparrow and Chris Gyngell discussed two aspects of enhancement. You can hear the podcast here (mp3). Rob Sparrow on ‘Enhancement and Obsolescence: Avoiding An “Enhanced Rat Race”‘: A claim about continuing technological progress plays an essential, if unacknowledged, role in the philosophical literature on “human enhancement”. Advocates for… Read More »Enhancement: Rat Race or Supermarket? (Podcasts)

Mind-controlled limbs and redefining the self

Image credit: University of Pittsburgh/UPMC

This week there were reports of the amazing advances being made in brain-computer interface (BCI) technology. Following just weeks of training, a 52-year old woman, paralysed from the neck down, was able to use her mind to control a robotic hand to pick up objects on a table, including cones, blocks and small balls, and put them down at another location. She was even able to use the hand to feed herself chocolate.

Having had two arrays of microelectrodes surgically implanted into her left motor cortex, Jan is wired up to a computer that has been programmed to interpret the signals her neurons emit. This computer then passes on the interpreted signals to the robotic arm, which moves in accordance with the signals in real time.

Aside from the awesomeness of the technology, the use of neuroprostheses such as this raises a whole host of interesting philosophical and ethical questions. Particularly as the technology gets more sophisticated and more integrated, the distinction between the machinery being used and the person using it will become increasingly blurred. In the video, Jan already describes how she went from having to ‘think’ the commands (‘clockwise, up, down, forward, back…’) to merely having to ‘look at the target’ to effect accurate movement of the arm. This phenomenon is sometimes labeled ‘transparency of use’, where a tool serves a person’s goals without itself being an object of effortful control.Read More »Mind-controlled limbs and redefining the self

Do we want “genetically modified children”? Yes, of course!

The agency that regulates fertility treatment and embryo research in the UK, the Human Fertilisation and Embryology Authority (HFEA), has asked for public views on two possible new forms of fertility treatment that promise to prevent the transmission of mitochondrial diseases to children. These diseases can be extremely severe, leading to (among other things) diabetes, deafness, progressive blindness, seizures, dementia, muscular dystrophy, and death.

Read More »Do we want “genetically modified children”? Yes, of course!

Yamanaka Wins Nobel Prize for Ethics

by Julian Savulescu, Uehiro Chair in Practical Ethics & Director, Oxford Uehiro Centre for Practical Ethics

Yamaka and Gurdon have jointly won the Nobel Prize for Physiology or Medicine, for the discovery that mature cells can be reprogrammed to become pluripotent: that is, already specialized cells can be taken, and using iPS technology, transformed into unspecialized stem cells, which can be used for research and treatment. This technology may ultimately allow us to replace embryonic stem cells entirely in research and treatment thus avoiding ethical issues raised by the destruction of embryos for this purpose.

This is not only a giant leap for science, it is a giant leap for mankind. Yamanaka and Gurdon have shown how science can be done ethically. Yamanaka has taken people’s ethical concerns seriously about embryo research and modified the trajectory of research into a path that is acceptable for all. He deserves not only a Nobel Prize for Medicine, but a Nobel Prize for Ethics.

Read More »Yamanaka Wins Nobel Prize for Ethics

Should you take ecstasy to improve your marriage? Not so fast …

Love drugs and science reporting in the media: Setting the record straight 

By Brian D. Earp, Julian Savulescu, and Anders Sandberg

Love. It makes the world go round. It is the reason we have survived as a species. It is the subject of our art, literature, and music—and it is largely the product of chemical reactions within the brain.

No wonder science is starting to unravel the ways in which we can influence it, and perhaps even control it.

Just as Darwin’s finding that we are descended from apes shocked people in the nineteenth century, so people will be shocked to find that our most lofty social ideal is something we share with our mammalian cousins and which is the subject of scientific scrutiny and even chemistry-book manipulation.

In 2008, two of us (Julian Savulescu and Anders Sandberg) published an article in the journal Neuroethics on the topic of “love drugs” – a term we use to refer to pharmacological interventions based on existing and future bio-technologies that could work to strengthen the bond between romantic partners. All three of us have an article just published in the journal Philosophy & Technology in which we build upon that earlier work. Interested readers will take the time to study those papers in full, but we have a feeling that much of the population will stop at a handful of media reports that have recently summarized our ideas, including at least one article that we think has the potential to mislead. Let us set the record straight.

Read More »Should you take ecstasy to improve your marriage? Not so fast …

Bold Private John Smith, VC, modified ‘t’ allele of TPH1 SNP rs2108977

By Charles Foster

There’s a significant association of PTSD symptoms with a particular allele, according to a recently published study from UCLA and Duke. Some of the ethical consequences are already being discussed.  One consequence might be military. One might be able to detect and filter out PTSD-vulnerable recruits. Perhaps that’s a kindness. It would certainly seem militarily prudent. There might be legitimate qualms about creating a biologically callous warrior-class, but you’re not creating its components – you’re just collecting them together. You might not want to go to their parties, and you might wonder about the mutually brutalizing effect of corralling them in a barracks, but the exercise is really only a scientifically more informed version of the selection that goes on in any event. It’s not very interesting ethically.
But what if a gene for PTSD-resistance could be inserted or artificially switched on? It doesn’t seem fanciful. Should the military be permitted (or perhaps even required) to PTSD-proof their personnel?Read More »Bold Private John Smith, VC, modified ‘t’ allele of TPH1 SNP rs2108977

In vitro meat, new technologies, and the “yuck factor”

In vitro meat, recently discussed on this blog by Julian Savulescu, is gradually becoming a reality. It holds great promise, notably considering that billons of animals are slaughtered for food every year, often after spending miserable lives in factory farms, and that the current production of meat contributes significantly to the emission of greenhouse gases. In spite of those facts, it seems highly unlikely that most meat-eaters will agree to give up meat anytime soon (though the success of the “meat-free Mondays” initiative in a number of different places should be saluted), yet they might well prove more willing to switch from traditionally produced meat to in vitro meat, if the latter were as healthy (or even healthier), reasonably priced, and tasted the same as the former.

 

Discussions of in vitro meat in the media most often cite the so-called “yuck factor” as a major obstacle to its general acceptance: i.e. the instinctive revulsion that many people feel at the idea of eating “unnatural” meat grown in a petri dish. I am inclined to be cautiously optimistic about the prospects of overcoming that obstacle: “unnatural” meat substitutes have already become popular among vegetarians, and some meat-eaters do consume them as well occasionally. Although in vitro meat should bear even more of an uncanny resemblance to the real thing than those substitutes (which might be why some people are revulsed by the idea), I would expect it to find success if issues of health and taste can be adequately dealt with. Now what if the yuck factor were to prove more of an issue than I anticipate? I believe the following points deserve to be emphasized:

Read More »In vitro meat, new technologies, and the “yuck factor”

H5N1: Why Open the Stable Door?

Professor Paul Keim, who chairs the US National Science Advisory Board for Biosecurity, recently recommended the censoring of research that described the mutations which led to the transformation of the H5N1 bird-flu virus into a form that can be transmitted between humans through droplets in breath (in ferrets, the number of mutations required is frighteningly… Read More »H5N1: Why Open the Stable Door?